Curcumin is a phytochemical (chemical naturally found in plants) obtained from turmeric (Curcuma longa L.) and is found to have anti-inflammatory properties. Now scientists are also working on the anti-cancer properties of this compound.
Curcumin has the ability to regulate different transcription factors, growth factors, inflammatory cytokines, protein kinases, and other enzymes, thereby can affect the different forms of cancer. This compound has been found to suppress
- cyclin D1, a proto-oncogene overexpressed in many cancers,
- adhesion molecules that are found to have an important role in tumor metastasis
- various inflammatory cytokines, including tumor necrosis factor
- angiogenesis that is an important step in the growth and metastasis of many cancers
“Currently, the molecular mechanisms of curcumin have been extensively elucidated, thereby giving insights to its anticancer, antioxidant and anti-inflammatory properties. As curcumin is shown to be non-toxic, further work is needed to substantiate the chemopreventive potentials of curcumin as the best alternative to chemotherapeutic agents which are deleterious to cancer patients,” Researchers concluded.
A Pramela Rani, V Saikishore (2013). The Potential Role of Curcumin in Cancer Prevention and Treatment. Research and Reviews: Journal of Pharmacy and Pharmaceutical Sciences.