Potential treatment for a condition of inflammatory hair loss

Improvement in the ailment from (a) to (c) after using calcipotriol (Credit: Ann Dermatol. 2012 August; 24(3): 341–344.)
Improvement in the ailment from (a) to (c) after using calcipotriol (Credit: Ann Dermatol. 2012 August; 24(3): 341–344.)

Main point:

Researchers reported, last year, that the topical use of calcipotriol, a synthetic derivative of vitamin D, could help in significant recovery from a condition of inflammatory hair loss known as Alopecia areata.

Published in:

Annals of Dermatology

Study Further:

Vitamin D is important in immune modulation in the skin while working on calcium regulation and bone metabolism. Alopecia areata has commonly been reported in the patients of vitamin D deficiency, vitamin D-resistant rickets, or vitamin D receptor (VDR) mutation.

“AA (alopecia areata) is difficult to treat. According to the guidelines of the British Association of Dermatologists, contact immunotherapy and corticosteroids are the most effective and best documented, but even these treatments often fail to induce hair growth6. Therefore, the need exists for more efficient treatments,” Researchers wrote.

In the study, researchers reported that a 7-year old boy showed significant recovery from alopecia areata having reduced VDR expression after topical use of calcipotriol. It was the first time that vitamin D was found to be significant treatment strategy for alopecia areata, according to researchers.

I think that the same chemical can be used for the patients of cancer, who are continuously using chemotherapeutic drugs and their immunity is in disturbed state resulting in alopecia areata.

Reference:

Kim, D., Lee, J., Kim, I., Choi, S., Lim, Y., Kim, H., Kim, B., & Kim, M. (2012). Successful Treatment of Alopecia Areata with Topical Calcipotriol Annals of Dermatology, 24 (3) DOI: 10.5021/ad.2012.24.3.341

Usman Zafar Paracha

Usman Zafar Paracha is a sort of entrepreneur. He is the author of "Color Atlas of Statistics", and the owner of an Android game "Faily Rocket."