Smoking women are at greater risk of developing skin cancer

Researchers have found that smoking is linked to skin cancer in women.

This study has been done by the researchers of the Moffitt Cancer Center in Tampa, Fla. U.S. and published online in the journal Cancer Causes and Control.

Researchers discovered that the women, who smoke tobacco, have higher chances of developing a specific form of cancer i.e. Squamous cell carcinoma (SCC). They based their results after working on 698 adult people in which 383 people were patients of basal cell carcinoma or squamous cell carcinoma of non-melanoma skin cancer (NMSC).

Researchers concluded that women who smoked at least 20 years are three-times more at the risk of developing SCC.

“Female current smokers have higher lung cancer risks than men. Women have been shown to have more active CYP enzyme activity in the lung, where CYP is responsible for metabolizing 70-80 percent of nicotine. In addition, the up-regulation of CYP by estrogen may play a role,” Dr. Dana Rollison and one of the researchers wrote.

“In conclusion, cigarette smoking was associated with NMSC, with significantly increased risks associated with increasing dose (cigarettes per day), duration (number of years smoked), and pack-years smoked,” scientists said. “Cigarette smoking is more strongly associated with SCC than BCC, particularly among women.”

Signs of Skin Cancer


Dana E. Rollison, Michelle R. Iannacone, Jane L. Messina, L. Frank Glass, Anna R. Giuliano, Richard G. Roetzheim, Basil S. Cherpelis, Neil A. Fenske, Kristen A. Jonathan and Vernon K. Sondak, (2011). Case–control study of smoking and non-melanoma skin cancer. Cancer Causes and Control, DOI: 10.1007/s10552-011-9872-y

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