Hearing impairment (HI) is associated with depression among American adults of all ages, especially women and individuals younger than 70 years.
JAMA Otolaryngology-Head & Neck Surgery
Chuan-Ming Li, M.D., Ph.D., of the National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Md., and colleagues.
Depression and HI are associated with personal, societal and economic burdens. However, the relationship between depression and HI has not been reported in a national sample of U.S. adults.
Children born to older fathers appear to be at higher risk for a variety of psychiatric problems and academic difficulties compared with children born to younger fathers, according to a study by Brian M. D’Onofrio, Ph.D., of Indiana University, Bloomington, and colleagues.
Previous research suggests advancing paternal age (APA) at childbearing is associated with genetic mutations during the development of sperm, which may cause an increased risk of child psychiatric, intellectual and academic problems, according to the study background.
The authors studied people born in Sweden from 1973 to 2001 and estimated the risk of psychiatric problems (autism, attention-deficit/hyperactivity disorder, psychosis, bipolar disorder, suicide attempt and substance abuse) and academic trouble (failing grades and low educational attainment of 10 years of less in school) using siblings, cousins and first-born cousins.
Patient-Centered Outcomes Research Institute sets prioritized research agenda for managing two diverse conditions
Two articles being published in Annals of Internal Medicine seek to set prioritized research agendas to fill the evidence gaps about two diverse conditions – bipolar disorder in young people and ductal carcinoma in situ (DCIS) in women.
Annals of Internal Medicine
Both conditions present similar challenges to physicians and patients because the diagnosis is often not clear-cut and typical treatments come with a trade-off of benefits and serious side effects.
Using a process described by the Patient-Centered Outcomes Research Institute (PCORI), researchers collaborated with various stakeholders including clinical experts, patients, and advocates to identify and rank the important gaps in knowledge that should be the focus of new research.
Prions can be notoriously destructive, spurring proteins to misfold and interfere with cellular function as they spread without control. New research from scientists at the Stowers Institute for Medical Research reveals that certain prion-like proteins, however, can be precisely controlled so that they are generated only in a specific time and place. These prion-like proteins are not involved in disease processes; rather, they are essential for creating and maintaining long-term memories.
“This protein is not toxic; it’s important for memory to persist,” says Stowers researcher Kausik Si, who led the study. To ensure that long-lasting memories are created only in the appropriate neural circuits, Si explains, the protein must be tightly regulated so that it adopts its prion-like form only in response to specific stimuli. He and his colleagues report on the biochemical changes that make that precision possible. Read more…
Elementary school lesson plans focused on healthy eating and physical activity delivered by older children to younger students appear effective at reducing waist size and improving knowledge of healthy living behaviors, according to a study by Robert G. Santos, Ph.D., of the Healthy Child Manitoba Office and the University of Manitoba, Canada, and colleagues.
Schools can be a good place to promote healthy living behaviors in children, and peer mentoring is a strategy for changing behavior in children, according to the study background.