Tag Archives: diagnosis

Increased Incidence of Thyroid Cancer Associated With Increased Diagnosis

Main Points:

The increased incidence of thyroid cancer appears to be associated with an “epidemic of diagnosis” and not disease, according to a study by Louise Davies, M.D., M.S., of the VA Medical Center, White River Junction, Vt., and H. Gilbert Welch, M.D., M.P.H., of the Dartmouth Institute for Health Policy & Clinical Practice, Hanover, N.H.

Published in:

JAMA Otolaryngology-Head & Neck Surgery

Study Further:

An increase in thyroid cancer previously has been reported, largely due to the detection of small papillary cancers, a common and less aggressive form of the disease, according to the study background.

The authors analyzed data for patients diagnosed with thyroid cancer from 1975 to 2009 in nine areas of the country using the Surveillance, Epidemiology, and End Results (SEER) program: Atlanta, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Utah, the San Francisco-Oakland area in California, and the Seattle-Puget Sound area of Washington.

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Video Intervention May Increase Skin Cancer Diagnosis in Older Men

Main Points:

Showing men a video on skin self-examination and skin awareness may help to increase the number of patients who receive whole-body clinical skin examinations (CSEs) from their physicians, which could increase skin cancer diagnosis in older men, according to a study by Monika Janda, Ph.D., of the Queensland University of Technology, Brisbane, Australia, and colleagues.

Published in:

JAMA Dermatology

Study Further:

In the United States, death rates from melanoma have decreased in women but have increased in men. Early detection is an important strategy and can be done with clinical or skin self-examination, according to the study background.

The researchers randomized 930 men (age 50 and older) to receive either a skin awareness video-based intervention and brochures or brochures only (control group). Outcome measures were those patients who reported a CSE, what type (skin spot, partial body or whole body), who initiated it, whether the physician noted any suspicious lesions and how the lesions were managed.

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Tiny device to capture, release and study cancer cells

Tiny device that can capture circulating tumor cells (Credit - RIKEN)

Tiny device that can capture circulating tumor cells (Credit: RIKEN)

Researchers have developed a device that captures/preserves and releases cancer cells circulating in the bloodstream.

This device has been developed by scientists from RIKEN Advanced Science Institute in Japan in collaboration with University of California Los Angeles and has been mentioned in the paper published online in the journal Advanced Materials.

This new device is a nanoscale Velcro-like device that can help not only in non-invasive diagnosis of cancer but also to study the mechanism involved in the spread of cancer in the body. With the help of this device doctors would be able to detect the cancer cells before their stay in the other organs. Moreover, the tumor cells would remain alive on the device, so the researchers would easily study them.

Blood passes through the device as a filter and the tumor cells adhere to the small molecules and separate them with 40%-70% of efficiency. Temperature at 37 degrees Celsius helps scientists to keep the tumor cells in tiny temperature-responsive polymer brushes or the temperature cooled to 4 degrees Celsius helps them to release and examine the cells.

Researchers wrote, “A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand-receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of cancer cells. Subsequently, these captured cells are released upon a physical stimulation with outstanding cell viability.” Continue reading