Depression With Atypical Features Associated With Obesity

Depression (Credit: Fakeelvis/Flickr)Main Point:

Major depressive disorder (MDD) with atypical features (including mood reactivity where people can feel better when positive things happen in life, increased appetite or weight gain) appears to be associated with obesity.

Published in:

JAMA Psychiatry

Authors:

Aurélie M. Lasserre, M.D., of Lausanne University Hospital, Switzerland, and colleagues.

Background:

MDD has tremendous public health impact worldwide. Obesity is another burden for public health. Understanding the mechanisms underlying the association between MDD and obesity is important. Continue reading

Weight Gain Following Antidepressant Use Examined

Antidepressants (Flickr)Main Point:

Modest differences exist between antidepressants with regard to weight gain among patients.

Published in:

JAMA Psychiatry

Authors:

Sarah R. Blumenthal, B.S., Massachusetts General Hospital, Boston, and colleagues.

Background:

Previous work has suggested an association between antidepressant use and weight gain. The potential health consequences could be significant because more than 10 percent of Americans are prescribed an antidepressant at any given time. Obesity is associated with a host of medical conditions, including cardiovascular disease, type 2 diabetes and high blood pressure. Continue reading