Posts Tagged ‘biotechnology’

Public defibrillator shortage helping to boost heart attack deaths away from hospital

Main Point:

Decade-long campaigns to increase public availability and awareness have gone unheeded.

Published in:

Heart

Study Further:

The restricted availability of defibrillators, and poor understanding of how to use them, are helping to boost the number of deaths from heart attacks occurring outside hospitals, suggests a study of one English county, published online in the journal Heart.

This is despite several campaigns to increase the numbers of these life-saving devices in public places, and the acknowledgement of the importance of their role in the English government’s Cardiovascular Disease Outcomes Strategy, published last March, say the authors.

Every minute of delay in administering resuscitation increases the risk of death after a heart attack by between 7% and 10%. Currently, only between 2% and 12% of those who have a heart attack outside hospital live to tell the tale, with the death toll reaching an annual 30,000 across the UK.

Read more…

Be the first to comment - What do you think?  Posted by saypeople - February 20, 2014 at 4:30 am

Categories: Medical, Technology   Tags: , , , , , , , , ,

Oral insulin to control sugar would soon be a reality

Oral Insulin could be a reality soon (Credit: Jupiterimages/Thinkstock)

Main Point:

Scientists have successfully administered and utilized insulin through mouth in rats and this would be a huge success against diabetes, if the same experiment will successfully be done on humans.

Published in:

Biomacromolecules

Study Further:

Something about Insulin therapy:

Scientists are working on and improving insulin therapy for diabetes and one of the most optimized way of insulin therapy could be administration through mouth, i.e. oral administration.

The concept of oral insulin is present since 1930s but it is a complicated thing, as insulin, being a protein, quickly destroys after coming in contact with stomach, and it has a huge size making it difficult to be absorbed through bloodstream.

Present Study:

In the present study, scientists worked on the above mentioned problems by packing insulin in tiny packets of lipids (fats) protecting insulin from stomach enzymes and by attaching it to folic acid to activate a transport mechanism, so that its absorption could be improved.

Scientists found that this strategy worked as effectively after oral administration in rats as injected insulin.

“In vivo pharmacodynamic and pharmacokinetic studies further revealed almost double hypoglycemia and approximately 20% relative bioavailability in comparison with subcutaneously administered standard insulin solution,” Scientists noted.

Although, the dose entering the bloodstream was small as compared to injected insulin but this newly developed oral formulation helped to control blood-sugar level for more than 18 hours as opposed to 6-8 hours after injection.

“Overall the proposed strategy is expected to contribute significantly in the field of designing ligand-anchored, polyelectrolyte-based stable systems in drug delivery,” Scientists wrote.

Sources:

Insulin pill may soon be a reality – The Conversation (http://goo.gl/YJrBQM)

Ashish Kumar Agrawal et al. (2013). Improved Stability and Antidiabetic Potential of Insulin Containing Folic Acid Functionalized Polymer Stabilized Multilayered Liposomes Following Oral Administration Biomacromolecules DOI: 10.1021/bm401580k

Be the first to comment - What do you think?  Posted by Usman Zafar Paracha - December 27, 2013 at 12:26 pm

Categories: Medical   Tags: , , , , , , , , ,

Experimental vaccine for the most deadly brain cancer / Research Suggestions

Gliobastoma (astrocytoma) WHO grade IV - MRI coronal view, post contrast. 15 year old boy (Credit: Christaras A/Wikimedia Commons)

Main Point:

Scientists have prolonged the survival of patients of brain tumor with the help of an experimental vaccine made from the tissue taken from the patient’s own cancerous part. Read more…

Be the first to comment - What do you think?  Posted by Usman Zafar Paracha - December 16, 2013 at 6:35 pm

Categories: Medical, Research   Tags: , , , , , , , , , , , ,

Which part of the brain detects fast motion in dim light?

Fast motion in dim light (Image credit: Jonathan Hedges/Flickr)

Main Point:

Scientists, for the first time, found the neural mechanism of sensing high-speed motion in faint light in the visual cortex of the brain. Read more…

Be the first to comment - What do you think?  Posted by Usman Zafar Paracha - November 12, 2013 at 6:39 pm

Categories: Medical, Research   Tags: , , , , , , , , , , ,

Bio-patch that enables the regeneration of bones

Bones (Image credit: Asja Boroš/Flickr)

Main Point:

Scientists have developed a new way to regrow missing or damaged bones with the help of “Bio-Patch”. Read more…

1 comment - What do you think?  Posted by Usman Zafar Paracha - November 10, 2013 at 1:54 pm

Categories: Medical, Technology   Tags: , , , , , , ,

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