Run (in a real meaning) away from cancer

Run (in a real meaning) to move away from cancer (Image source: fbi.gov)
Run (in a real meaning) to move away from cancer (Image source: fbi.gov)

Main Points:

Running (exercise) could reduce the growth of cancer, i.e. incidences of tumor and tumor size decrease because of running.

Published in:

Cell Metabolism

Study Further:

In a study, researchers worked on the mice model of cancer. They exposed the mice to cancer, and checked the affect of running (exercise). They reported in the study that the risk of cancer as well as its recurrence could be reduced by regular exercise.

Study shows that exercise helps in the reduction of tumor incidence as well as growth in many mice models. In the study, it has been reported that only 31% of the running mice developed tumors, whereas 75% of the control mice developed tumors. Moreover, tumor volume reduced by 58% in the running mice and tumor weight reduced by 56%.

Researchers found that exercise increases immunity, thereby helping in fighting against cancer. Exercise elevates Natural killer (NK) cell infiltration that is helpful in controlling tumor growth, while the reduction of NK cells result in increased tumor growth. Moreover, it has been reported that mobilization of NK cells because of exercise is caused by epinephrine.

“Together, these results link exercise, epinephrine, and IL-6 (Interleukin 6 that is used to activate immune response) to NK cell mobilization and redistribution, and ultimately to control of tumor growth,” Researchers noted in the paper.

Source:

Line Pedersen, Manja Idorn, Gitte H. Olofsson, Britt Lauenborg, Intawat Nookaew, Rasmus Hvass Hansen, Helle Hjorth Johannesen, Jürgen C. Becker, Katrine S. Pedersen, Christine Dethlefsen, Jens Nielsen, Julie Gehl, Bente K. Pedersen, Per thor Straten, Per (2016). Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution Cell Metabolism

Usman Zafar Paracha

Usman Zafar Paracha is Assistant Professor, Pharmaceutics, in Hajvery University, Lahore, Pakistan.