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lang="en-US">Electronic Monitoring Documents Lack of Medication Adherence in Patients with Glaucoma | SayPeople

Electronic Monitoring Documents Lack of Medication Adherence in Patients with Glaucoma

Main Point:

Electronic monitoring to measure medication adherence by patients with glaucoma documented that a sizable number of patients did not regularly use the eye drops prescribed to them.

Published in:

JAMA Ophthalmology


Michael V. Boland, M.D., Ph.D., of the Wilmer Eye Institute at Johns Hopkins University, Baltimore, Md., and colleagues.


Topical medications for glaucoma lower intraocular pressure and can delay or slow the progression of the eye disease. Medication adherence is important.

How the Study Was Conducted:

Patients who were treated with once-daily prostaglandin eye drops were recruited from a university-based glaucoma clinic. Patients were given a container with an electronic cap in which to store their eye drops. The cap recorded each time the container was opened.


Of the 407 patients who completed the three-month adherence assessment, 337 (82.8 percent) took their medication correctly on at least 75 percent of days. The other 70 patients (17.2 percent) (deemed nonadherent) were less likely to be able to name their glaucoma medication, less likely to agree that remembering to use the medication was easy, and more likely to agree with the sentiment that eye drops can cause problems.


“Given that most patients are taking their eye drops as prescribed, identifying patients at risk of nonadherence is a critical step. The results from the patient questions and demographic factors may therefore be useful in creating risk calculators that could find those patients most in need of intervention.”


Michael V. Boland MD, PhD, Dolly S. Chang MD, PhD, Travis Frazier MD, Ryan Plyler BS, David S. Friedman MD, MPH, PhD. Electronic Monitoring to Assess Adherence With Once-Daily Glaucoma Medications and Risk Factors for Nonadherence: The Automated Dosing Reminder Study. JAMA Ophthalmol. 2014; 132(7):-. doi:10.1001/jamaophthalmol.2014.856

Editor’s Note:

This study was supported by a grant from the Microsoft Be Well Fund. Please see article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Media Advisory:

To contact author Michael V. Boland, M.D., Ph.D., call Stephanie Desmon at 410-955-8665 or email

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