New dye to effectively diagnose the diseases and to work on the cure

Novel dyes to enhance medical imaging (Credit: University of Copenhagen/ Jes Andersen)
Novel dyes to enhance medical imaging (Credit: University of Copenhagen/ Jes Andersen)

Main Point:

Researchers have developed new type of dyes, namely aza-oxa-trangulenium dyes that can be used more effectively than the conventional fluorescent dyes used in imaging technologies.

Study Further:

Imaging technologies require certain types of dyes for the diagnosis of diseases or for research of the new treatment strategies for the diseases. These dyes also need to be optimized for not only effectiveness but also for the expensiveness.

“Our dyes are ten times better, far cheaper and easier to use. The latter I believe, will lead to expanded opportunities and broadened use, by physicians and researchers in developing countries, for example.” Said Thomas Just Sørensen.

Usually, tissues and other structures of the body lights up for about 10 nenoseconds after exposure to light and the light-life of the ordinary dye is also the same but triangulenium dyes enhance the production of light for about 100 nanoseconds. This ability of the new dye to reduce the shining of the cells and the tissues can help to reduce the background “light noise”. This gives a broader time for the researchers to work on the tissues and diseases.

This dye is also cost effective as it does not need specialized equipments to see the dyes in tissue samples. An ordinary microscope and a lens from a pair of polarized sunglasses can help to see the samples.

“I know that our dye is better, but biologists and physicians don’t. Therefore, we are giving the dye away to anyone that wants to perform a comparison test. Someone who needs to assess the health of sick people wouldn’t dare to rely on an untested substance. Only when several researchers have shown triangulenium dyes to perform just as effectively as its predecessors can we hope for our substance to become more widely adopted,” concludes Thomas Just Sørensen.



Usman Zafar Paracha

Usman Zafar Paracha is Assistant Professor, Pharmaceutics, in Hajvery University, Lahore, Pakistan.