Genetic test for chances of Schizophrenia would come in the next 3-5 years; Research


Researchers have developed a possible test that would detect the risk of schizophrenia.

This research has been published online in the journal of Molecular Psychiatry.

Schizophrenia is a mental disorder that is found to be linked to a set of genetic variations, stress and several other environmental factors affecting the development and connections of the brain. According to the National Institute of Mental Health , schizophrenia affects about 1% of Americans.

[hana-code-insert name=’StumbleUpon’ /][hana-code-insert name=’Reddit’ /]Researchers have worked on the most likely cause of the disease related to a comprehensive set of genes. They have taken information from genome-wide association studies, personalized studies and several other sources in order to develop the list of genes. After taking the list, they tested genetic risk in four different groups of people and found that the test was accurate in about 66% of people.

Alexander B. Niculescu III, MD, PHD, associate professor of psychiatry and medical neuroscience at the Indiana University School of Medicine, Indianapolis, said that the test could be commercialized within the next 3-5 years, after some further trials.

The researchers said that the test could be helpful for children in high-risk families. However, this test is helpful in getting a prediction only. “In the end, your genes are not your destiny.” Said Niculescu.


M Ayalew, H Le-Niculescu, D F Levey, N Jain, B Changala, S D Patel, E Winiger, A Breier, A Shekhar, R Amdur, D Koller, J I Nurnberger, A Corvin, M Geyer, M T Tsuang, D Salomon, N J Schork, A H Fanous, M C O’Donovan and A B Niculescu, (2012). Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Molecular Psychiatry, doi:10.1038/mp.2012.37

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